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Supercritical CO2 herb oil extraction machine

CO2 herb oil extraction machine


Reasonable structure

Short connections, high strength, light vibration, to ensure safe and efficient, in order to achieve the reduction of production costs and extraction speed.


Frequency conversion technology to reduce the power consumption of high-pressure pump by 30%. In addition, automatic heat pump technology, can reduce heat consumption by 50%. Fully automatic control, the entire operation is more efficient and conveniental, shorten the non-working energy-consuming time, after running more than 10% energy can be saved.

Automatic operation

Extraction kettle lid mining and quick-open structure, the use of system gas lid, double extraction kettle alternating work, changing the tank time of not more than 5 minutes, saving a lot of time than the traditional methods, but also reduce the labor intensity.

Early warning and monitoring

System over-voltage, over-temperature, overtime, equipment anomalies have alarm and emergency measures, the system has a total of six safety valves, all high-pressure valves are monitored, open the extraction tank by zero pressure test control to prevent misuse caused by the danger of contact with the material in the equipment used in all stainless steel (SS304), fully able to meet the production requirements of food or medicine.

Automatic Control

In the domestic supercritical extraction equipment, with the production of the detection, regulation, control records, alarm and all other functions, and already have a mature control of independent copyright software.


TypeSpecificationPressureCombined type
1L1L*150Mpa1 extraction vessels & 2 separators
2L2L*150Mpa1 extraction vessels & 2 separators
5L5L*150Mpa1 extraction vessels & 2 separators
6L 5L+1L50Mpa2 extraction vessels & 2 separators
10L5L*250Mpa2 extraction vessels & 2 separators
20L10L*240Mpa2 extraction vessels & 2 separators
50L25L*240Mpa2 extraction vessels & 2 separators
120L30L*440Mpa4 extraction vessels & 3 separators
100L50L*240Mpa2 extraction vessels & 2 separators
200L-A50L*440Mpa4 extraction vessels & 3 separators
200L-B100L*240Mpa2 extraction vessels & 2 separators
300L-A50L*640Mpa6 extraction vessels & 3 separators
300L-B100L*340Mpa3 extraction vessels & 3 separators
300L-C150L*240Mpa2 extraction vessels & 3 separators
400L200L*240Mpa3 extraction vessels & 3 separators
600L-A150L*440Mpa4 extraction vessels & 3 separators
600L-B200L*340Mpa3 extraction vessels & 3 separators
800L200L*440Mpa3 extraction vessels & 3 separators
900L300L*335MPa3 extraction vessels & 3 separators
1200L300L*435MPa4 extraction vessels & 3 separators
1800L600L*335MPa3 extraction vessels & 3 separators
2100L700L*335MPa3 extraction vessels & 3 separators
6000L3000L*235MPa2 extraction vessels & 3 separators
450L150L*340MPa3 extraction vessels & 3 separators
1500L500L*335MPa3 extraction vessels & 3 separators
1800L600L*335MPa3 extraction vessels & 3 separators

Extraction vessel and pressure can be customized freely. Optional fractionation column.

Photos of herb oil supercritical CO2 extraction equipment

Supercritical fluid and supercritical CO2 extraction

Supercritical CO2 extraction technology

When a substance is above its critical temperature and critical pressure, it becomes a single state, and this single state is called a supercritical fluid.
In the supercritical state, the supercritical fluid is contacted with the substance to be separated. By controlling different temperatures, pressures, and different types and contents of cosolvents, the supercritical fluid can selectively adjust the polarity, boiling point, and The molecular weight components are extracted sequentially.

This extraction method is called Supercritical Extraction (SFE). It has a density close to a liquid and a dissolving power similar to a liquid, and it has a viscosity and a diffusion coefficient close to that of a gas.
This means that the supercritical fluid has a high mass transfer rate and the ability to quickly reach the extraction equilibrium.

Supercritical fluid extraction process

The supercritical fluid extraction process is basically composed of two parts: supercritical fluid extraction of the solute and the separation of the extracted solute and the supercritical fluid. According to the different separation methods, it can be divided into three different processes. That is, isothermal separation process, isobaric separation process and adsorption separation process.

Main factors affecting supercritical CO2 extraction


Under a certain pressure, increasing the temperature can increase the volatility of the extracts, and the concentration of SCF increases, which increases the extraction quantity; but on the other hand, increasing the temperature decreases the density of SCF and the dissolving ability, resulting in a decrease in the extraction quantity. Therefore, the temperature effect is more complicated, and the above two aspects need to be considered comprehensively.


When the extraction temperature is constant, increasing the pressure will increase the density of the SCF, the strength of the solvent and the solubility of the solute. For different substances, the extraction pressure is different.

Extract particle size

The particles of the extract should be suitable. The smaller the particle size, the larger the contact area with SCF, which is beneficial to increase the extraction speed; but at the same time, too small particle size will block the sieve holes, cause frictional heat, increase the temperature of the system, and destroy the active materials.

Supercritical CO2 extraction of herb

Extraction of herb

The extraction, separation, and purification of active ingredients in herbal medicines have always been an important part and difficulty in herbal research.
Because of the low content of active ingredients in herbal medicines; active ingredients and inactive ingredients coexist; similar structural components interfere with many, traditional extraction and separation The methods often have low extraction rates, are difficult to separate, and even cause pollution.

CO2 extraction of herb

Supercritical CO2 fluid extraction technology is a high-tech material separation and refining technology with two processes of refinement and extraction that has emerged in recent years.
Because of its convenient operation, low energy consumption, no pollution, high separation capacity, and no solvent residues, it is widely used in the fields of medicine, food, and environmental protection.

At present, carbon dioxide supercritical extraction technology is often used to extract different kinds of medicinal ingredients in herbal medicines, such as volatile oils, alkaloids, terpenes, propanophenols, quinones, anthropus derivatives, and other ingredients.
Supercritical CO2 extraction can also pre-treat herbal materials to remove toxic or interfering components.

Cosolvent for CO2 fluid extraction

CO2 is a non-polar substance with selective dissolution. Supercritical CO2 fluids are excellent for low-molecular, low-polar, lipophilic, and low-boiling components such as volatile oils, hydrocarbons, esters, lactones, ethers, epoxy compounds, etc. Solubility.

The active ingredients of most herbal medicines are compounds with more polar groups and larger molecular weights. Supercritical CO2 fluids are relatively difficult to extract large molecules and substances with more polar groups, and co-solvents need to be added to change their solubility.
Commonly used co-solvents include methanol, ethanol, acetone, ethyl acetate and so on.


Extracting biologically active ingredients from natural animals, plants, and minerals for human health is an important part of pharmaceutical research. Most traditional extraction methods are inefficient.

Supercritical CO2 fluid extraction equipment is a revolution in herbal medicine extraction. However, most of the active ingredient molecules of herbal medicines are polar, and pure supercritical CO2 fluid extraction is not suitable for the extraction of all active ingredients. The addition of co-solvents improves the selectivity and application range of the extracted ingredients, and improves the extraction efficiency, more and more widely used in herbal research.

Method for supercritical CO2 extraction of herbal

At present, carbon dioxide supercritical extraction technology is mostly used to extract different kinds of medicinal ingredients in Chinese herbal medicines, such as volatile oils, alkaloids, sugars, propanophenols, diospyros, onion derivatives and other ingredients.

Extraction of volatile oil

CO2 extraction method of evening primrose oil

The supercritical CO2 fluid extracts evening primrose oil from the evening primrose seeds. As a result, the color and transparency of the evening primrose essential oil and the content of y-linolenic acid with significant physiological activity are better than the solvent method.

CO2 extraction method of volatile oil of angelica

Supercritical CO2 fluid extracts the volatile oil of Angelica sinensis. The pressure is 30MPa, the temperature is 44°C, and the time is 3h. The yield is 115%. After GC-MS analysis of the obtained essential oil, a series of alkanes that cannot be obtained by conventional methods are separated and identified for the first time. There are 28 ingredients including glutinous rice, organic acids and esters.

Extraction of flavonoids

Flavonoids are rich in resources. Traditional methods mainly use alcohol, alkaline water, alkaline alcohol, hot water, etc., after extraction, and then separate them according to their polarity, acidity, molecular size, and special structure.
However, these methods all have the disadvantages of serious pollution, high loss of active ingredients, low efficiency and high cost, and SFE technology can overcome the above shortcomings and ensure quality.

CO2 extraction method of ginkgo biloba

Orthogonal test was used to investigate the extraction process of SFE technology for ginkgo biloba leaves and kaempferin and kaempferol. It was found that the extraction temperature was 60°C, the extraction pressure was 42MPa, the static extraction time was 4min, the dynamic extraction volume was 4ml, and 0.2ml ethanol had the best effect.

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