With the development of pharmacological and toxicological research on the bioactive components of ginkgo biloba, its medicinal functions have gradually been explored.
Ginkgo flavonoids have the effects of expanding coronary blood vessels, antispasmodic, and scavenging free radicals in the body. They can be used to treat coronary heart disease and have analgesic and anti-aging effects.
Ginkgolides and white lactones are unique components of Ginkgo biloba and are the natural medicines of choice for the treatment of cardiovascular and cerebrovascular diseases and neurological diseases. Ginkgolide is a very effective platelet activating factor antagonist and has significant effects on preventing and treating atherosclerosis, hypertension, cerebral ischemia, etc.
Ginkgolide has a unique effect on the treatment of neurological diseases such as Alzheimer’s disease and encephalopathy. In addition, ginkgo phenol and ginkgol, which represent the harmful components of ginkgo biloba, have anti-cancer effects in addition to pesticides.
Supercritical Carbon Dioxide Extraction of Ginkgo Flavonoids
Since the content of total lactones in the standard extract of Ginkgo biloba leaves is relatively low, the molecular structure of impurities is similar to the medicinal components, and the polarity difference is small, the extraction and separation process of the effective components is more complicated.
Supercritical carbon dioxide extraction is a new separation method.
It has many advantages such as high extraction efficiency, no residual toxicity of solvents, natural active ingredients and heat-sensitive ingredients that are not easy to decompose and destroy, maximum retention of the natural characteristics of the extract, and selective separation. Supercritical fluids are called “super solvents”.
The technology of supercritical carbon dioxide extraction of ginkgo flavonoids uses the characteristics of supercritical fluids.